Peter Wipf Selected Research

JP4-039

1/2020	Fanconi Anemia Mouse Genotype-specific Mitigation of Total Body Irradiation by GS-Nitroxide JP4-039.
11/2019	Amelioration of Mucositis in Proton Therapy of Fanconi Anemia Fanca-/- Mice by JP4-039.
3/2017	Induction of TGF-β by Irradiation or Chemotherapy in Fanconi Anemia (FA) Mouse Bone Marrow Is Modulated by Small Molecule Radiation Mitigators JP4-039 and MMS350.
2/2016	Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2(-/-) (C57BL/6) Mice.
7/2014	Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.
7/2014	Esophageal radioprotection by swallowed JP4-039/F15 in thoracic-irradiated mice with transgenic lung tumors.
11/2011	Amelioration of radiation esophagitis by orally administered p53/Mdm2/Mdm4 inhibitor (BEB55) or GS-nitroxide.
7/2010	Small molecule GS-nitroxide ameliorates ionizing irradiation-induced delay in bone wound healing in a novel murine model.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Peter Wipf Research Topics

Disease

67	Neoplasms (Cancer) 03/2022 - 04/2002
16	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 11/2008
8	Fanconi Anemia (Fanconi's Anemia) 01/2020 - 11/2011
7	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2005
7	Ischemia 10/2018 - 02/2007
6	Carcinogenesis 01/2017 - 04/2002
5	Necrotizing Enterocolitis 09/2021 - 06/2015
5	Inflammation (Inflammations) 01/2021 - 06/2015
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 07/2013
4	Parkinson Disease (Parkinson's Disease) 01/2021 - 07/2013
4	Ovarian Neoplasms (Ovarian Cancer) 01/2021 - 01/2018
4	Fibrosis (Cirrhosis) 11/2020 - 05/2013
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 11/2020 - 05/2013
4	Mucositis 11/2019 - 01/2014
4	Lambert-Eaton Myasthenic Syndrome (Lambert-Eaton Syndrome) 01/2018 - 12/2012
4	Colonic Neoplasms (Colon Cancer) 12/2015 - 07/2004
3	Huntington Disease (Huntington's Disease) 01/2022 - 11/2012
3	Neoplasm Metastasis (Metastasis) 12/2020 - 01/2018
3	Lung Neoplasms (Lung Cancer) 06/2020 - 01/2009
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 11/2015
3	Colorectal Neoplasms (Colorectal Cancer) 10/2018 - 05/2014
3	Brain Injuries (Brain Injury) 11/2017 - 10/2012
3	Squamous Cell Carcinoma of Head and Neck 07/2017 - 11/2011
3	Esophagitis 01/2014 - 11/2010
3	Malaria 09/2011 - 10/2009
3	Alzheimer Disease (Alzheimer's Disease) 12/2008 - 01/2005
3	Hemorrhagic Shock 01/2008 - 02/2007
2	Hypoxia (Hypoxemia) 01/2022 - 03/2006
2	Weight Loss (Weight Reduction) 01/2021 - 11/2012
2	Tinnitus 01/2021 - 01/2016
2	Starvation 01/2021 - 01/2018
2	Paralysis (Palsy) 12/2019 - 05/2019
2	Neuromuscular Diseases (Neuromuscular Disease) 01/2018 - 12/2012

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2004
13	nitroxylIBA 03/2022 - 01/2008
11	Pharmaceutical PreparationsIBA 01/2021 - 12/2009
10	Biological ProductsIBA 01/2022 - 04/2002
9	XJB-5-131IBA 01/2022 - 09/2007
9	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 01/2016
8	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 09/2007
8	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021 - 01/2007
8	JP4-039IBA 01/2020 - 07/2010
8	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 12/2019 - 01/2003
8	protein kinase DIBA 03/2015 - 05/2010
7	Protein Tyrosine PhosphatasesIBA 12/2020 - 01/2018
6	AndrogensIBA 01/2021 - 02/2013
6	JMS-053IBA 01/2021 - 02/2018
5	MMS350IBA 01/2019 - 05/2013
5	AntioxidantsIBA 01/2017 - 09/2007
5	LipidsIBA 09/2016 - 09/2002
4	Messenger RNA (mRNA)IBA 01/2022 - 05/2013
4	Dual-Specificity PhosphatasesIBA 01/2021 - 04/2002
4	LuciferasesIBA 01/2020 - 11/2013
4	enzalutamideIBA 01/2020 - 01/2016
4	Molecular Chaperones (Chaperone, Molecular)IBA 01/2019 - 12/2004
4	Cardiolipins (Cardiolipin)IBA 01/2017 - 07/2010
4	Gramicidin (Gramicidin A)FDA LinkGeneric 07/2014 - 09/2007
4	TubulinIBA 01/2014 - 04/2002
4	PX-866IBA 01/2009 - 07/2004
3	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 01/2013
3	Toll-Like Receptor 4IBA 01/2021 - 06/2015
3	Amino Acids FDA Link 01/2021 - 01/2018
3	sulfoxideIBA 11/2020 - 05/2013
3	Adenosine Triphosphatases (ATPase)IBA 03/2020 - 03/2008
3	Prostate-Specific Antigen (Semenogelase)IBA 01/2020 - 01/2016
3	Acetylcholine (Acetylcholine Chloride)FDA Link 12/2019 - 10/2010
3	Drinking WaterIBA 01/2019 - 11/2013
3	abirateroneIBA 01/2019 - 01/2016
3	DNA (Deoxyribonucleic Acid)IBA 10/2018 - 02/2010
3	EnzymesIBA 10/2018 - 04/2002
3	Calcium Channels (Calcium Channel)IBA 01/2018 - 12/2012
3	TEMPOIBA 02/2016 - 02/2007
3	Phospholipids (Phosphatides)FDA LinkGeneric 02/2015 - 09/2002
3	Tyrosine (L-Tyrosine)FDA Link 05/2014 - 01/2005
3	kb-NB142-70IBA 05/2014 - 05/2010
3	Mefloquine (Lariam)FDA LinkGeneric 09/2011 - 10/2009
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 10/2021 - 01/2016
2	Toll-Like Receptors (Toll-Like Receptor)IBA 09/2021 - 01/2021
2	2'-fucosyllactoseIBA 01/2021 - 01/2021
2	Potassium Channels (Potassium Channel)IBA 01/2021 - 01/2016
2	6'-sialyllactoseIBA 01/2021 - 01/2021
2	OligosaccharidesIBA 01/2021 - 01/2021
2	Ergot AlkaloidsIBA 01/2021 - 07/2016
2	RNA (Ribonucleic Acid)IBA 01/2020 - 05/2013
2	Green Fluorescent ProteinsIBA 01/2020 - 05/2019
2	LigandsIBA 01/2020 - 12/2019
2	Dopamine (Intropin)FDA LinkGeneric 12/2019 - 09/2013
2	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 12/2019 - 01/2018
2	SulfurIBA 01/2019 - 08/2016
2	SynucleinsIBA 01/2019 - 07/2013
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 02/2015
2	Oxygen (Dioxygen)IBA 11/2018 - 07/2010
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 10/2018 - 02/2010
2	PlatinumIBA 01/2018 - 02/2015
2	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 02/2015
2	CalciumIBA 01/2018 - 02/2015

Therapy/Procedure

20	Therapeutics 01/2021 - 02/2007
10	Castration 01/2022 - 01/2016
7	Radiotherapy 11/2018 - 01/2011
3	Drug Therapy (Chemotherapy) 03/2017 - 03/2014